Genetic abnormalities can arise during cell line generation, routine cell culture, and gene editing. Cell lines need to maintain their genomic integrity if they are to be used for research and clinical applications. It is essential to routinely test and catalog the genetic alterations when working with cell lines.

• At the initiation of a new or unique cell line
• As standard quality control at regular intervals during the culturing and passaging processes
• When cell lines perform inconsistently or with unexpected results
• In cases where recurrent chromosomal abnormalities have previously been detected in a specific cell line

Even if a cell line is shown to be authentic, it can lose key characteristics with prolonged passaging. Hence, the genomic integrity of cell lines in cultures should be frequently assessed.

The reviewers of scientific papers generally regard karyotyping as the most-trusted method of verifying a cell line's chromosomal makeup.

Most cell types are accepted including cancer lines. Please contact the lab to confirm acceptability for karyotyping before sending samples. 

Samples can be dropped off in the lab or shipped to us (please see our Ordering and Sample Submission pages for complete instructions).

Our typical turnaround time is between 5 to 10 days. More complex cell lines may take a little longer to analyze and sign out.

Yes, at an extra charge. 

We can provide both electronic or hard copies of the report. We are also happy to personalize the report format as per your requirements.

• Human
• Mouse
• Rat
• Chimpanzee
• Many others (please contact us with details)

• GeneCode caters specifically to the research community, unlike the majority of Cytogenetics labs, which prioritize clinical workflow.
• Direct access to the personnel working with your samples provides quick solutions to your research study questions/problems. We can rapidly customize study criteria and reports to meet your testing and publication needs.
• Our prices are competitive and reasonable. We also offer special discounted prices for long-term research projects.